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Skin hydration and renewal with bioremodelling treatments

Bioremodelling treatments are injectable therapies designed to improve skin quality, hydration, elasticity and firmness. They support the skin’s natural remodelling processes, with results that develop progressively for a fresher, firmer and naturally revitalised appearance.

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What are bioremodelling treatments?
What are bioremodelling treatments?

Injectable bioremodelling treatments focus on improving the quality and condition of the skin and underlying tissues. Depending on the product, they can support hydration, elasticity, firmness and tissue quality, with results developing gradually over time.

Unlike traditional hyaluronic acid fillers, these treatments are not primarily intended to add volume or significantly reshape facial contours. They are suited to patients seeking a fresher, firmer and more revitalised appearance while preserving their natural features.

What concerns can bioremodelling treatments address?

Depending on the product and individual indication, they may be suitable for:

  • dehydrated skin
  • delicate or thin skin
  • loss of elasticity
  • early skin laxity
  • reduced skin firmness and density
  • skin showing signs of ageing or reduced quality
  • selected areas of the neck, décolletage and body
  • patients seeking natural-looking improvement without traditional volumisation
Bioremodelling treatments at Dermique

Profhilo® Body

Profhilo® Body is specifically developed for areas of the body where the skin shows loss of elasticity, firmness or tissue quality. It may be used in areas such as the abdomen, upper arms and thighs, depending on the individual indication and skin assessment.

Profhilo® Body

Profhilo Body – Profhilo Body Kit box

Profhilo® Body is specifically developed for areas of the body where the skin shows loss of elasticity, firmness or tissue quality. It may be used in areas such as the abdomen, upper arms and thighs, depending on the individual indication and skin assessment.

Profhilo®

Profhilo® is a high-concentration hyaluronic acid injectable treatment developed for skin bioremodelling. It is used to improve hydration, elasticity and overall skin quality without the aim of creating traditional filler-like volume.

It may be suitable for delicate, dehydrated or lax skin, particularly on the face and neck, following individual assessment.

Profhilo®

Profhilo – product box

Profhilo® is a high-concentration hyaluronic acid injectable treatment developed for skin bioremodelling. It is used to improve hydration, elasticity and overall skin quality without the aim of creating traditional filler-like volume.

It may be suitable for delicate, dehydrated or lax skin, particularly on the face and neck, following individual assessment.

Profhilo Structura®

Profhilo Structura® is an injectable treatment developed to address age-related changes in superficial facial adipose tissue and provide support where changes in facial structure and contour have occurred.

It may be suitable for selected patients experiencing changes in tissue support and facial contours who are looking for a regenerative approach without traditional facial volumisation.

Profhilo Structura®

Profhilo Structura – box and syringe

Profhilo Structura® is an injectable treatment developed to address age-related changes in superficial facial adipose tissue and provide support where changes in facial structure and contour have occurred.

It may be suitable for selected patients experiencing changes in tissue support and facial contours who are looking for a regenerative approach without traditional facial volumisation.

Karisma®

Karisma® is a bioregenerative injectable treatment combining hyaluronic acid with recombinant human collagen. It is designed to support skin quality, elasticity and tissue structure and may be considered for delicate, lax, photo-damaged or tired-looking skin.

The focus is on progressive improvement in skin quality for a smoother, fresher and naturally revitalised appearance.

Karisma®

Karisma – woman in a black dress holding a Karisma box

Karisma® is a bioregenerative injectable treatment combining hyaluronic acid with recombinant human collagen. It is designed to support skin quality, elasticity and tissue structure and may be considered for delicate, lax, photo-damaged or tired-looking skin.

The focus is on progressive improvement in skin quality for a smoother, fresher and naturally revitalised appearance.

Bioremodelling treatments at Dermique
What to expect during your treatment

Before treatment, the skin, treatment area and degree of dehydration, laxity or tissue change are carefully assessed. Product selection depends on the individual indication — whether the focus is hydration, bioremodelling, structural support or improvement in overall skin quality.

The selected product is administered through a series of precisely placed injections using a technique appropriate to the product and treatment area. The procedure typically takes around 20–30 minutes.

Combining bioremodelling treatments
Bioremodelling treatments may be combined with other aesthetic procedures as part of a personalised treatment plan, with each treatment addressing a different aspect of facial ageing or skin quality.

Bioremodelling treatments + botulinum toxin

Botulinum toxin is used to soften dynamic expression lines by reducing targeted muscle activity, while bioremodelling treatments focus on hydration, elasticity and skin quality.

Bioremodelling treatments + dermal fillers

Dermal fillers can restore volume, provide structural support and refine facial contours, while bioremodelling treatments focus primarily on skin and tissue quality. The two approaches may complement each other when both volume loss and changes in skin quality are present.

Bioremodelling treatments + device-based and laser treatments

When concerns include skin texture, enlarged pores, laxity or photoageing, bioremodelling treatments may be incorporated into a broader treatment plan alongside selected laser or device-based procedures.

The appropriate combination, timing and sequence are determined individually.

A refined approach to aesthetics
Personalised bioremodelling treatments focused on hydration, elasticity and progressive improvement in skin quality.
Frequently asked questions
What is the difference between bioremodelling treatments and dermal fillers?
Dermal fillers are primarily used to restore volume, provide structural support and refine specific facial contours. Bioremodelling treatments are not primarily intended for traditional facial contouring or volumisation. Instead, they focus on improving hydration, elasticity and overall skin and tissue quality.

Some products within this category have specific structural indications, so the most appropriate treatment is selected according to individual anatomy and treatment goals.
Both Profhilo® and skin boosters can improve hydration and overall skin quality, but they differ in their formulation, properties and treatment protocols.

Skin boosters are generally used to improve hydration, fine lines and skin texture through multiple small injections. Profhilo® is a specific hyaluronic acid-based bioremodelling treatment designed to improve hydration and support skin elasticity and firmness without traditional volumisation.

The most appropriate option depends on the condition of the skin and the desired outcome.
The recommended treatment protocol depends on the specific product, treatment area and individual indication. Different bioremodelling products have different recommended protocols, and maintenance treatment may be considered where appropriate.

Your individual treatment plan will be determined following consultation and assessment.
Results develop progressively. Improvements in hydration and freshness may become noticeable first, while changes in elasticity, firmness and overall skin quality develop over the following weeks.

The timeline varies according to the product used, treatment area and individual response.
Treatment is based on skin condition and individual indication rather than age alone. In younger patients, selected treatments may be considered for concerns such as dehydration or early changes in skin quality.

In more mature skin, the focus may be on elasticity, firmness, tissue quality and visible signs of skin ageing. Suitability is always determined following individual assessment.
Downtime is generally minimal, although this varies depending on the product and technique used. Small raised areas at injection points, redness, swelling, tenderness or bruising may occur temporarily.

With some products and injection techniques, small visible bumps at the injection sites are expected and gradually subside.
Suitability depends on the specific product and individual medical history. Treatment may not be appropriate in the presence of active infection or inflammation in the treatment area, active herpes or known hypersensitivity to product components.

Pregnancy, breastfeeding, medications and relevant medical conditions should be discussed during consultation. Treatment is recommended only after an individual medical assessment confirms that it is appropriate.

Atrophic scars

Atrophic scars are indented scars that most commonly appear following acne or other inflammatory conditions. They are caused by a loss of collagen and uneven skin regeneration.

Appropriate treatment methods

At Dermique, we don’t treat acne scars using just one technique. Where necessary, we combine: