Bioremodelling treatments are injectable therapies designed to improve skin quality, hydration, elasticity and firmness. They support the skin’s natural remodelling processes, with results that develop progressively for a fresher, firmer and naturally revitalised appearance.
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Injectable bioremodelling treatments focus on improving the quality and condition of the skin and underlying tissues. Depending on the product, they can support hydration, elasticity, firmness and tissue quality, with results developing gradually over time.
Unlike traditional hyaluronic acid fillers, these treatments are not primarily intended to add volume or significantly reshape facial contours. They are suited to patients seeking a fresher, firmer and more revitalised appearance while preserving their natural features.
Depending on the product and individual indication, they may be suitable for:
Profhilo® Body
Profhilo® Body is specifically developed for areas of the body where the skin shows loss of elasticity, firmness or tissue quality. It may be used in areas such as the abdomen, upper arms and thighs, depending on the individual indication and skin assessment.
Profhilo® Body
Profhilo® Body is specifically developed for areas of the body where the skin shows loss of elasticity, firmness or tissue quality. It may be used in areas such as the abdomen, upper arms and thighs, depending on the individual indication and skin assessment.
Profhilo®
Profhilo® is a high-concentration hyaluronic acid injectable treatment developed for skin bioremodelling. It is used to improve hydration, elasticity and overall skin quality without the aim of creating traditional filler-like volume.
It may be suitable for delicate, dehydrated or lax skin, particularly on the face and neck, following individual assessment.
Profhilo®
Profhilo® is a high-concentration hyaluronic acid injectable treatment developed for skin bioremodelling. It is used to improve hydration, elasticity and overall skin quality without the aim of creating traditional filler-like volume.
It may be suitable for delicate, dehydrated or lax skin, particularly on the face and neck, following individual assessment.
Profhilo Structura®
Profhilo Structura® is an injectable treatment developed to address age-related changes in superficial facial adipose tissue and provide support where changes in facial structure and contour have occurred.
It may be suitable for selected patients experiencing changes in tissue support and facial contours who are looking for a regenerative approach without traditional facial volumisation.
Profhilo Structura®
Profhilo Structura® is an injectable treatment developed to address age-related changes in superficial facial adipose tissue and provide support where changes in facial structure and contour have occurred.
It may be suitable for selected patients experiencing changes in tissue support and facial contours who are looking for a regenerative approach without traditional facial volumisation.
Karisma®
Karisma® is a bioregenerative injectable treatment combining hyaluronic acid with recombinant human collagen. It is designed to support skin quality, elasticity and tissue structure and may be considered for delicate, lax, photo-damaged or tired-looking skin.
The focus is on progressive improvement in skin quality for a smoother, fresher and naturally revitalised appearance.
Karisma®
Karisma® is a bioregenerative injectable treatment combining hyaluronic acid with recombinant human collagen. It is designed to support skin quality, elasticity and tissue structure and may be considered for delicate, lax, photo-damaged or tired-looking skin.
The focus is on progressive improvement in skin quality for a smoother, fresher and naturally revitalised appearance.
Profhilo® Body
Profhilo® Body is specifically developed for areas of the body where the skin shows loss of elasticity, firmness or tissue quality. It may be used in areas such as the abdomen, upper arms and thighs, depending on the individual indication and skin assessment.
Profhilo®
Profhilo® is a high-concentration hyaluronic acid injectable treatment developed for skin bioremodelling. It is used to improve hydration, elasticity and overall skin quality without the aim of creating traditional filler-like volume.
It may be suitable for delicate, dehydrated or lax skin, particularly on the face and neck, following individual assessment.
Profhilo Structura®
Profhilo Structura® is an injectable treatment developed to address age-related changes in superficial facial adipose tissue and provide support where changes in facial structure and contour have occurred.
It may be suitable for selected patients experiencing changes in tissue support and facial contours who are looking for a regenerative approach without traditional facial volumisation.
Karisma®
Karisma® is a bioregenerative injectable treatment combining hyaluronic acid with recombinant human collagen. It is designed to support skin quality, elasticity and tissue structure and may be considered for delicate, lax, photo-damaged or tired-looking skin.
The focus is on progressive improvement in skin quality for a smoother, fresher and naturally revitalised appearance.
Before treatment, the skin, treatment area and degree of dehydration, laxity or tissue change are carefully assessed. Product selection depends on the individual indication — whether the focus is hydration, bioremodelling, structural support or improvement in overall skin quality.
The selected product is administered through a series of precisely placed injections using a technique appropriate to the product and treatment area. The procedure typically takes around 20–30 minutes.
Bioremodelling treatments + botulinum toxin
Botulinum toxin is used to soften dynamic expression lines by reducing targeted muscle activity, while bioremodelling treatments focus on hydration, elasticity and skin quality.
Bioremodelling treatments + dermal fillers
Dermal fillers can restore volume, provide structural support and refine facial contours, while bioremodelling treatments focus primarily on skin and tissue quality. The two approaches may complement each other when both volume loss and changes in skin quality are present.
Bioremodelling treatments + device-based and laser treatments
When concerns include skin texture, enlarged pores, laxity or photoageing, bioremodelling treatments may be incorporated into a broader treatment plan alongside selected laser or device-based procedures.
The appropriate combination, timing and sequence are determined individually.
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Atrophic scars
Atrophic scars are indented scars that most commonly appear following acne or other inflammatory conditions. They are caused by a loss of collagen and uneven skin regeneration.
Appropriate treatment methods
At Dermique, we don’t treat acne scars using just one technique. Where necessary, we combine:

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