Collagen biostimulators are injectable treatments that work beyond simply restoring volume. They stimulate the skin’s natural remodelling processes and support new collagen production, gradually improving skin density, elasticity and structure.
At Dermique, we select from different types of collagen biostimulators according to the treatment area, skin quality, degree of laxity, volume loss and desired outcome. The focus is on progressive, natural-looking results that develop over time.
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Sculptra®
Sculptra® is a poly-L-lactic acid (PLLA) collagen biostimulator designed to stimulate the gradual production of new collagen. It may be suitable for patients experiencing volume loss, skin laxity or reduced tissue density who are looking for progressive, natural-looking rejuvenation rather than an immediate or dramatic change.
Sculptra®
Sculptra® is a poly-L-lactic acid (PLLA) collagen biostimulator designed to stimulate the gradual production of new collagen. It may be suitable for patients experiencing volume loss, skin laxity or reduced tissue density who are looking for progressive, natural-looking rejuvenation rather than an immediate or dramatic change.
Radiesse®
Radiesse® is a calcium hydroxylapatite (CaHA)-based injectable that can provide structural support while also stimulating collagen production. Depending on the treatment approach, it may be used to improve contours, skin firmness and overall skin quality in selected areas of the face and body.
The most appropriate indication and technique are determined following individual assessment.
Radiesse®
Radiesse® is a calcium hydroxylapatite (CaHA)-based injectable that can provide structural support while also stimulating collagen production. Depending on the treatment approach, it may be used to improve contours, skin firmness and overall skin quality in selected areas of the face and body.
The most appropriate indication and technique are determined following individual assessment.
Juvelook®
Juvelook® is a hybrid injectable treatment that combines hyaluronic acid with poly-D,L-lactic acid (PDLLA) to support hydration and collagen stimulation.
It is particularly suited to improving skin quality in delicate areas, including the eye contour, where it may help address fine lines, thin skin and an overall tired appearance without the aim of creating significant volume.
Juvelook®
Juvelook® is a hybrid injectable treatment that combines hyaluronic acid with poly-D,L-lactic acid (PDLLA) to support hydration and collagen stimulation.
It is particularly suited to improving skin quality in delicate areas, including the eye contour, where it may help address fine lines, thin skin and an overall tired appearance without the aim of creating significant volume.
HArmonyCa™
HArmonyCa™ is a hybrid injectable combining hyaluronic acid with calcium hydroxylapatite (CaHA). The hyaluronic acid component provides an immediate volumising and structural effect, while CaHA supports the gradual stimulation of collagen production.
It may be suitable for selected patients seeking improved facial support, definition and skin firmness alongside progressive improvement in skin quality.
HArmonyCa™
HArmonyCa™ is a hybrid injectable combining hyaluronic acid with calcium hydroxylapatite (CaHA). The hyaluronic acid component provides an immediate volumising and structural effect, while CaHA supports the gradual stimulation of collagen production.
It may be suitable for selected patients seeking improved facial support, definition and skin firmness alongside progressive improvement in skin quality.
Sculptra®
Sculptra® is a poly-L-lactic acid (PLLA) collagen biostimulator designed to stimulate the gradual production of new collagen. It may be suitable for patients experiencing volume loss, skin laxity or reduced tissue density who are looking for progressive, natural-looking rejuvenation rather than an immediate or dramatic change.
Radiesse®
Radiesse® is a calcium hydroxylapatite (CaHA)-based injectable that can provide structural support while also stimulating collagen production. Depending on the treatment approach, it may be used to improve contours, skin firmness and overall skin quality in selected areas of the face and body.
The most appropriate indication and technique are determined following individual assessment.
Juvelook®
Juvelook® is a hybrid injectable treatment that combines hyaluronic acid with poly-D,L-lactic acid (PDLLA) to support hydration and collagen stimulation.
It is particularly suited to improving skin quality in delicate areas, including the eye contour, where it may help address fine lines, thin skin and an overall tired appearance without the aim of creating significant volume.
HArmonyCa™
HArmonyCa™ is a hybrid injectable combining hyaluronic acid with calcium hydroxylapatite (CaHA). The hyaluronic acid component provides an immediate volumising and structural effect, while CaHA supports the gradual stimulation of collagen production.
It may be suitable for selected patients seeking improved facial support, definition and skin firmness alongside progressive improvement in skin quality.
Before treatment, we assess the face, skin quality and the areas requiring structural support or remodelling. Product selection is an important part of the treatment plan, as different biostimulators vary in composition, tissue behaviour, injection technique and the way their results develop over time.
The selected product is precisely placed in predetermined areas according to the individual treatment plan. A local or topical anaesthetic may be used where appropriate for additional comfort.
Temporary swelling, redness, tenderness or bruising may occur following treatment.
Collagen biostimulators + hyaluronic acid fillers
Hyaluronic acid fillers can restore volume, structure and facial contours, while collagen biostimulators focus on gradually improving tissue quality and supporting collagen production. The two approaches may complement each other in selected patients with volume loss, reduced definition or changes in skin quality.
Collagen biostimulators + botulinum toxin
Botulinum toxin is used to reduce the appearance of dynamic lines by temporarily modifying targeted muscle activity, while collagen biostimulators focus on skin structure, density and firmness.
When appropriately planned, the combination can address different aspects of facial ageing while maintaining a natural-looking result.
Collagen biostimulators + Morpheus8 Burst
Morpheus8 Burst combines microneedling with radiofrequency energy to promote tissue remodelling and improve skin firmness and texture. Collagen biostimulators may complement this approach by supporting progressive collagen production and improvement in tissue quality.
The timing and sequence of the treatments are determined individually.
Collagen biostimulators + skin boosters
For dehydrated or delicate skin, skin boosters and collagen biostimulators may be incorporated into the same overall treatment plan to address different aspects of skin quality.
Skin boosters primarily focus on hydration and elasticity, while collagen biostimulators target progressive tissue remodelling and collagen production. The appropriate sequence depends on the products used and the individual condition of the skin.
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Atrophic scars
Atrophic scars are indented scars that most commonly appear following acne or other inflammatory conditions. They are caused by a loss of collagen and uneven skin regeneration.
Appropriate treatment methods
At Dermique, we don’t treat acne scars using just one technique. Where necessary, we combine:

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